I think the main concern is disk space, you would want to follow some quota when having manu databases, Also ifyou full text each db that is taking disk space as well. Don't forget that view index run faster if given its own disk partion but make sure is not smaller than a few GB.
IBM had tens of thousands or like 11K, of mail miles on one server when Lotusphere had a large conference attendence, I have a friend with 40,000 on linux - he is an ASP solution provider. remember that if evertyone has the same design db then use single source as that saves space as well.
I think the main concern is disk space, you would want to follow some quota when having manu databases, Also ifyou full text each db that is taking disk space as well. Don't forget that view index run faster if given its own disk partion but make sure is not smaller than a few GB.
IBM had tens of thousands or like 11K, of mail miles on one server when Lotusphere had a large conference attendence, I have a friend with 40,000 on linux - he is an ASP solution provider. remember that if evertyone has the same design db then use single source as that saves space as well.
HTH